ILDR1

Across TCGA cell cohorts, ILDR1 mutation is significantly associated with the RNA expression of many other genes, with 96 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ILDR1-associated genes across cancer lineages are H2BC1, H2AC1, and KRTAP10-1. Each is linked with ILDR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ILDR1-to-partner and partner-to-ILDR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, H2BC1 grouped by ILDR1-low versus ILDR1-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ILDR1→partner) and Y-score (partner→ILDR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	H2BC1 →	+0.433	+5.977	<.001	.001	3	1
SOFT_TISSUE	H2AC1 →	+0.193	+5.977	<.001	.001	3	1
SOFT_TISSUE	KRTAP10-1 →	+0.034	+5.369	.002	.004	3	1
SOFT_TISSUE	GAGE12E →	+0.090	+4.930	<.001	.008	3	1
CNS	HES3 →	+0.044	+5.321	<.001	.005	3	1
LARGE_INTESTINE	ACSM6 →	+0.025	+3.584	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 96 associations by consensus.

H2BC1 by ILDR1 expression — SOFT_TISSUE

Explore this box plot interactively →