IL7R

Across TCGA patient cohorts, IL7R protein abundance is significantly associated with the RNA expression of many other genes, with 1,476 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IL7R-associated genes across cancer lineages are RARRES2, GNAI2, and PDZRN3. Each is linked with IL7R in more than 1 cancer types. Because this analysis shows association rather than direction, both IL7R-to-partner and partner-to-IL7R results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL7R versus RARRES2 in LSCC, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL7R→partner) and Y-score (partner→IL7R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RARRES2 →	+0.686	+0.346	<.001	<.001	3	2
LSCC	GNAI2 →	+0.287	+0.333	<.001	<.001	3	2
LSCC	PDZRN3 →	+0.666	+0.389	.001	.001	3	2
LSCC	TMEM204 →	+0.758	+0.498	<.001	<.001	3	2
LSCC	ADAM19 →	+0.604	+0.362	<.001	<.001	3	2
LSCC	GYPC →	+0.522	+0.384	.005	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,476 associations by consensus.

IL7R vs RARRES2 — LSCC

Explore this scatter interactively →