IL7R

Across TCGA pan-cancer cohorts, IL7R RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated IL7R data layer compared with 12 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher IL7R RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated IL7R expression acts as an unfavorable survival marker, although some lineages such as LUAD and SKCM show a favorable association.

LUAD, SKCM, and UVM are the cancer types where IL7R RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	All	0.739	0.593	<.001	96	view →
SKCM	OS	Median	All	0.837	0.720	<.001	89	view →
UVM	OS	Quartile	All	0.358	0.917	<.001	56	view →
BRCA	DFS	Median	All	0.584	0.490	.003	55	view →
LGG	OS	Median	All	0.381	0.511	<.001	43	view →
LIHC	OS	Median	All	0.855	0.709	<.001	40	view →
UCEC	DFS	Median	III,IV	0.681	0.424	.004	32	view →
ESCA	DFS	Quartile	All	0.597	0.262	.005	31	view →
LUSC	DFS	Median	II,III,IV	0.294	0.463	.016	23	view →
STAD	DFS	Tertile	All	0.477	0.623	.008	20	view →
GBM	DFS	Tertile	All	0.204	0.430	.013	18	view →
HNSC	DFS	Quartile	III,IV	0.461	0.211	.007	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

IL7R–LUAD (DFS)

Open the LUAD breakdown →