IL17RB

Across TCGA cell cohorts, IL17RB mutation is significantly associated with the RNA expression of many other genes, with 299 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible IL17RB-associated genes across cancer lineages are GNGT1, CRYAA, and OR10T2. Each is linked with IL17RB in more than 1 cancer types. Because this analysis shows association rather than direction, both IL17RB-to-partner and partner-to-IL17RB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GNGT1 grouped by IL17RB-low versus IL17RB-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL17RB→partner) and Y-score (partner→IL17RB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GNGT1 →	+0.060	+4.551	<.001	.004	3	1
BLOOD_Leukemia	CRYAA →	+0.059	+4.705	<.001	.003	3	1
BLOOD_Leukemia	OR10T2 →	+0.584	+4.276	.005	.007	3	1
BLOOD_Leukemia	TLE7 →	+0.032	+4.969	<.001	.003	3	1
OVARY	ASB17 →	+0.014	+4.222	<.001	.006	3	1
OVARY	OR2M4 →	+0.062	+5.115	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 299 associations by consensus.

GNGT1 by IL17RB expression — BLOOD_Leukemia

Explore this box plot interactively →