IL17RB

Across TCGA pan-cancer cohorts, IL17RB RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated IL17RB data layer compared with 3 for mutation status and 2 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher IL17RB RNA is associated with better overall survival. In most high-consensus cancer types, elevated IL17RB expression acts as an unfavorable survival marker, although some lineages such as KIRC and COAD show a favorable association.

KIRC, COAD, and SKCM are the cancer types where IL17RB RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.720	0.534	<.001	142	view →
COAD	OS	Tertile	III,IV	0.933	0.614	<.001	75	view →
SKCM	DFS	Tertile	All	0.248	0.131	<.001	54	view →
READ	OS	Tertile	II,III,IV	1.000	0.794	.006	53	view →
LIHC	DFS	Tertile	III,IV	0.226	0.469	.001	45	view →
ACC	OS	Median	All	0.722	1.000	.001	44	view →
KIRP	OS	Tertile	All	0.980	0.876	.002	41	view →
HNSC	DFS	Median	IV	0.717	0.563	.001	41	view →
BRCA	OS	Median	All	0.977	0.947	.002	34	view →
LGG	DFS	Tertile	All	0.620	0.787	<.001	33	view →
KICH	DFS	Tertile	II,III,IV	0.512	0.891	.015	24	view →
ESCA	OS	Median	All	0.659	1.000	.020	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

IL17RB–KIRC (OS)

Open the KIRC breakdown →