IGLV5-37

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGLV5-37 mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IGLV5-37-associated genes across cancer lineages are NUDT4P2, MIR378D1, and RNA5SP189. Each is linked with IGLV5-37 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGLV5-37-to-partner and partner-to-IGLV5-37 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLV5-37→partner) and Y-score (partner→IGLV5-37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECNUDT4P2 →+0.091+3.747<.001.00331
SKCMMIR378D1 →+0.497+7.816<.001.00831
LUSCRNA5SP189 →+0.502+7.924<.001.00831
LUSCRNU1-139P →+0.518+7.924<.001.00831
LUSCUSP9YP10 →+0.064+7.924<.001.00831
LUSCRNU7-87P →+0.763+7.924<.001.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

Exploration