IGLV2-18

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGLV2-18 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,037 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGLV2-18-associated proteins across cancer lineages are MZB1, SEPTIN1, and WAS. Each is linked with IGLV2-18 in more than 9 cancer types. Because this analysis shows association rather than direction, both IGLV2-18-to-partner and partner-to-IGLV2-18 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLV2-18→partner) and Y-score (partner→IGLV2-18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMMZB1 →+1.387+0.932<.001<.001310
GBMSEPTIN1 →+0.796+0.958<.001.005310
GBMWAS →+0.460+0.653<.001<.00139
OVWIPF1 →+0.438+1.537<.001<.00139
OVLPXN →+0.819+2.102<.001<.00139
OVLSP1 →+0.741+1.819<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,037 associations by consensus.

Exploration