Across TCGA patient cohorts, IGKV7-3 RNA expression is significantly associated with the RNA expression of many other genes, with 6,933 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible IGKV7-3-associated genes across cancer lineages are IGKV3D-20, IGKV3D-11, and IGKV3D-15. Each is linked with IGKV7-3 in more than 31 cancer types. Because this analysis shows association rather than direction, both IGKV7-3-to-partner and partner-to-IGKV7-3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV7-3→partner) and Y-score (partner→IGKV7-3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THCA	IGKV3D-20 →	+3.850	+0.971	<.001	<.001	3	32
THCA	IGKV3D-11 →	+2.861	+0.975	<.001	<.001	3	32
THCA	IGKV3D-15 →	+2.810	+0.974	<.001	<.001	3	32
CHOL	IGLV2-18 →	+3.353	+1.124	<.001	.001	3	31
THCA	IGHV2-5 →	+3.008	+0.948	<.001	<.001	3	31
THCA	IGHV2-26 →	+3.717	+0.956	<.001	<.001	3	31

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,933 associations by consensus.

Exploration

IGKV7-3 survival (RNA) · tumor vs normal (RNA) · all IGKV7-3 data types