Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, IGKV6D-21 mutation is significantly associated with the RNA expression of many other genes, with 85 significant associations in total. UCEC shows the largest number of these associations.
The most reproducible IGKV6D-21-associated genes across cancer lineages are SEPTIN14P2, TRAV37, and MIR4499. Each is linked with IGKV6D-21 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGKV6D-21-to-partner and partner-to-IGKV6D-21 results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (IGKV6D-21→partner) and Y-score (partner→IGKV6D-21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.