IGKV2D-38

Across TCGA patient cohorts, IGKV2D-38 RNA expression is significantly associated with the RNA expression of many other genes, with 2,381 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible IGKV2D-38-associated genes across cancer lineages are IGKV2OR2-7D, IGKV2OR22-3, and IGKV2OR2-2. Each is linked with IGKV2D-38 in more than 10 cancer types. Because this analysis shows association rather than direction, both IGKV2D-38-to-partner and partner-to-IGKV2D-38 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGKV2D-38 versus IGKV2OR2-7D in BLCA, with a Pearson correlation of 0.39.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV2D-38→partner) and Y-score (partner→IGKV2D-38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	IGKV2OR2-7D →	+0.919	+0.018	<.001	<.001	3	11
SKCM	IGKV2OR22-3 →	+2.494	+0.027	<.001	.002	2	10
THCA	IGKV2OR2-2 →	+0.938	+0.038	<.001	<.001	3	9
UVM	IGHJ2P →	+1.505	+0.155	<.001	<.001	3	9
SARC	IGKV2-26 →	+2.555	+0.014	<.001	.003	3	8
KIRP	IGHV3OR16-15 →	+1.788	+0.009	<.001	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,381 associations by consensus.

IGKV2D-38 vs IGKV2OR2-7D — BLCA

Explore this scatter interactively →