IGKV2D-14

Across TCGA patient cohorts, IGKV2D-14 RNA expression is significantly associated with the RNA expression of many other genes, with 4,941 significant associations in total. ESCA shows the largest number of these associations.

The most reproducible IGKV2D-14-associated genes across cancer lineages are IGKV1D-32, IGLV3-2, and MIR516A2. Each is linked with IGKV2D-14 in more than 9 cancer types. Because this analysis shows association rather than direction, both IGKV2D-14-to-partner and partner-to-IGKV2D-14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGKV2D-14 versus IGKV1D-32 in THCA, with a Pearson correlation of 0.27.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV2D-14→partner) and Y-score (partner→IGKV2D-14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THCA	IGKV1D-32 →	+0.585	+0.093	<.001	<.001	3	10
SKCM	IGLV3-2 →	+0.588	+0.014	<.001	.008	3	10
ESCA	MIR516A2 →	+0.973	+0.084	<.001	<.001	3	8
ESCA	MIR520A →	+0.896	+0.117	<.001	<.001	3	7
ESCA	MIR527 →	+1.167	+0.058	<.001	<.001	3	7
ESCA	IGKV2D-19 →	+0.933	+0.057	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,941 associations by consensus.

IGKV2D-14 vs IGKV1D-32 — THCA

Explore this scatter interactively →