Q-omics provides the consensus-scored IGKV2D-14 profile across patient tissues and cancer cell-line models. IGKV2D-14 expression is associated with patient survival in 9 of 34 cancer types, with the highest sampling consensus in UVM. Additionally, IGKV2D-14 RNA expression shows 4,941 significant gene co-expression associations, with the highest sampling consensus in ESCA. Together, these results highlight UVM, and ESCA as cancer lineages where IGKV2D-14 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes IGKV2D-14 survival associations across molecular data types. IGKV2D-14 RNA expression shows survival associations in the most cancer types (9). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

IGKV2D-14 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	9	UVM (99)	view →

This table ranks reproducible IGKV2D-14 RNA expression–survival associations across cancer types. High IGKV2D-14 expression shows unfavorable associations in UVM, KIRC, ESCA, STAD, LUAD and OV. The UVM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UVM as the clearest survival context for IGKV2D-14 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	All	0.104	0.858	<.001	99	view →
KIRC	DFS	Tertile	III,IV	0.200	0.758	<.001	78	view →
ESCA	OS	Tertile	II,III,IV	0.253	0.711	<.001	72	view →
STAD	DFS	Tertile	III,IV	0.155	0.588	<.001	66	view →
LUAD	DFS	Tertile	II,III,IV	0.211	0.666	<.001	54	view →
OV	DFS	Tertile	II,III,IV	0.313	0.543	.047	36	view →

Pink = unfavorable, green = favorable. all 9 lineages →

IGKV2D-14-UVM (OS)

Kaplan–Meier survival curve for IGKV2D-14 RNA expression in UVM: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with IGKV2D-14 in patient tissues and cancer cell lines. In patient samples, IGKV2D-14 shows the broadest associations at the RNA and protein expression levels, with ESCA recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	4,941	ESCA (2414)	view →
Function (RNA)	4,693	STAD (4226)	view →