IGKV1D-17

Across TCGA patient cohorts, IGKV1D-17 RNA expression is significantly associated with the RNA expression of many other genes, with 6,666 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible IGKV1D-17-associated genes across cancer lineages are IGKV2-29, IGKV1OR2-6, and IGHV3OR16-6. Each is linked with IGKV1D-17 in more than 32 cancer types. Because this analysis shows association rather than direction, both IGKV1D-17-to-partner and partner-to-IGKV1D-17 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGKV1D-17 versus IGKV2-29 in CHOL, with a Pearson correlation of 0.66.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV1D-17→partner) and Y-score (partner→IGKV1D-17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CHOL	IGKV2-29 →	+2.742	+1.892	<.001	<.001	3	33
LUSC	IGKV1OR2-6 →	+2.283	+2.169	<.001	<.001	3	33
STAD	IGHV3OR16-6 →	+1.609	+1.712	<.001	<.001	3	33
HNSC	IGKV6-21 →	+2.775	+1.670	<.001	<.001	3	33
HNSC	IGHV4-28 →	+3.034	+1.609	<.001	<.001	3	33
HNSC	IGKV1OR2-108 →	+2.813	+1.673	<.001	<.001	3	33

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,666 associations by consensus.

IGKV1D-17 vs IGKV2-29 — CHOL

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