IGHVIV-44-1

Across TCGA patient cohorts, IGHVIV-44-1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,787 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible IGHVIV-44-1-associated GO terms across cancer lineages are B cell mediated immunity, Antibacterial humoral response, and Immune system development. Each is linked with IGHVIV-44-1 in more than 13 cancer types. Because this analysis shows association rather than direction, both IGHVIV-44-1-to-partner and partner-to-IGHVIV-44-1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, B cell mediated immunity grouped by IGHVIV-44-1-low versus IGHVIV-44-1-high in THCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHVIV-44-1→partner) and Y-score (partner→IGHVIV-44-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THCA	B cell mediated immunity →	+0.103	+0.024	<.001	<.001	3	13
THCA	Antibacterial humoral response →	+0.140	+0.020	<.001	<.001	3	13
ESCA	Immune system development →	+0.062	+0.142	<.001	<.001	3	13
ESCA	B cell activation →	+0.072	+0.130	<.001	.003	2	14
ESCA	Alpha-beta T cell activation →	+0.069	+0.150	<.001	.002	3	13
ESCA	Leukocyte apoptotic process →	+0.075	+0.183	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,787 associations by consensus.

B cell mediated immunity by IGHVIV-44-1 expression — THCA

Explore this box plot interactively →