IGHV3-38

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGHV3-38 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible IGHV3-38-associated genes across cancer lineages are Neutrophils and CMP. Each is linked with IGHV3-38 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGHV3-38-to-partner and partner-to-IGHV3-38 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHV3-38→partner) and Y-score (partner→IGHV3-38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADNeutrophils →+0.007+3.197.009.04832
UCECCMP →+0.039+2.818.036.03712
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

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