IGHV3-30

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGHV3-30 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible IGHV3-30-associated genes across cancer lineages are CMP. Each is linked with IGHV3-30 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGHV3-30-to-partner and partner-to-IGHV3-30 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CMP grouped by IGHV3-30-low versus IGHV3-30-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHV3-30→partner) and Y-score (partner→IGHV3-30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMCMP →+0.054+3.074.013.03831
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

CMP by IGHV3-30 expression — SKCM

Box plot of CMP in IGHV3-30-low vs IGHV3-30-high samples in SKCM.

Explore this box plot interactively →

Exploration