IGHV2-70

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGHV2-70 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,355 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGHV2-70-associated proteins across cancer lineages are MZB1, ARHGAP15, and LSP1. Each is linked with IGHV2-70 in more than 9 cancer types. Because this analysis shows association rather than direction, both IGHV2-70-to-partner and partner-to-IGHV2-70 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGHV2-70 versus MZB1 in OV, with a Pearson correlation of 0.65.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHV2-70→partner) and Y-score (partner→IGHV2-70) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVMZB1 →+1.493+3.300<.001<.001310
OVARHGAP15 →+0.606+2.973<.001<.00139
OVLSP1 →+0.677+2.548<.001.00139
LSCCCD38 →+0.945+1.986<.001<.00139
BRCADOCK2 →+0.548+1.998<.001<.00139
OVIL16 →+0.623+2.718<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,355 associations by consensus.

IGHV2-70 vs MZB1 — OV

Per-sample scatter of IGHV2-70 vs MZB1 in OV (Pearson r = 0.65).

Explore this scatter interactively →

Exploration