IGHV1-69D

Across TCGA patient cohorts, IGHV1-69D RNA expression is significantly associated with the protein abundance of many other proteins, with 13,190 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGHV1-69D-associated proteins across cancer lineages are MZB1, DOCK2, and IL16. Each is linked with IGHV1-69D in more than 9 cancer types. Because this analysis shows association rather than direction, both IGHV1-69D-to-partner and partner-to-IGHV1-69D results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGHV1-69D versus MZB1 in OV, with a Pearson correlation of 0.70.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHV1-69D→partner) and Y-score (partner→IGHV1-69D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MZB1 →	+1.472	+3.520	<.001	<.001	3	10
LSCC	DOCK2 →	+0.559	+1.674	<.001	<.001	3	10
OV	IL16 →	+0.623	+3.239	<.001	<.001	3	10
OV	LPXN →	+0.837	+3.852	<.001	<.001	3	10
OV	LSP1 →	+0.785	+3.650	<.001	<.001	3	10
LSCC	RASAL3 →	+0.478	+1.760	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,190 associations by consensus.

IGHV1-69D vs MZB1 — OV

Explore this scatter interactively →