IFIT1B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IFIT1B mutation is significantly associated with the RNA expression of many other genes, with 2,216 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IFIT1B-associated genes across cancer lineages are TRIM43, ASB10, and MINAR2. Each is linked with IFIT1B in more than 1 cancer types. Because this analysis shows association rather than direction, both IFIT1B-to-partner and partner-to-IFIT1B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFIT1B→partner) and Y-score (partner→IFIT1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADTRIM43 →+0.286+3.252<.001.00932
LUADASB10 →+0.047+3.899.008.00432
READMINAR2 →+0.083+4.361<.001.00632
SKCMSENP3-EIF4A1 →+0.241+3.796<.001<.00132
UCECMYO19 →+0.555+3.724<.001<.00132
UCECPHF5A →+0.650+4.169<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,216 associations by consensus.

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