HTR2C

Across TCGA cell cohorts, HTR2C RNA expression is significantly associated with the RNA expression of many other genes, with 3,672 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible HTR2C-associated genes across cancer lineages are ADAMTS20, CDH8, and POU6F2. Each is linked with HTR2C in more than 7 cancer types. Because this analysis shows association rather than direction, both HTR2C-to-partner and partner-to-HTR2C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HTR2C versus ADAMTS20 in LUNG_SCLC, with a Pearson correlation of 0.45.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HTR2C→partner) and Y-score (partner→HTR2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	ADAMTS20 →	+1.088	+0.736	<.001	.004	2	8
LUNG_NSCLC_LUSC	CDH8 →	+2.315	+1.042	<.001	<.001	3	6
LUNG_SCLC	POU6F2 →	+1.332	+0.727	.005	.008	1	8
OESOPHAGUS	SLC5A12 →	+0.962	+1.020	<.001	<.001	3	5
PANCREAS	GABRG2 →	+1.226	+0.392	<.001	<.001	3	5
LUNG_SCLC	RBM11 →	+1.407	+0.846	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,672 associations by consensus.

HTR2C vs ADAMTS20 — LUNG_SCLC

Explore this scatter interactively →