HTR1D

Across TCGA cell cohorts, HTR1D RNA expression is significantly associated with the RNA expression of many other genes, with 6,669 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible HTR1D-associated genes across cancer lineages are AXL, EGFR, and UPP1. Each is linked with HTR1D in more than 5 cancer types. Because this analysis shows association rather than direction, both HTR1D-to-partner and partner-to-HTR1D results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HTR1D versus AXL in LIVER, with a Pearson correlation of 0.64.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HTR1D→partner) and Y-score (partner→HTR1D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	AXL →	+4.973	+1.783	<.001	.001	3	6
SKIN	EGFR →	+3.591	+0.798	<.001	.001	3	6
BONE	UPP1 →	+2.614	+1.105	<.001	<.001	3	5
LUNG_NSCLC_LUSC	GPR39 →	+1.537	+1.083	.004	.003	2	6
LUNG_NSCLC_LUSC	BCAR3 →	+2.210	+1.237	<.001	.006	2	6
BREAST	OSMR →	+2.374	+0.766	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,669 associations by consensus.

HTR1D vs AXL — LIVER

Explore this scatter interactively →