HSPB11

Across TCGA patient cohorts, HSPB11 protein abundance is significantly associated with the RNA expression of many other genes, with 13,371 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HSPB11-associated genes across cancer lineages are CDC20, UROD, and CXCL14. Each is linked with HSPB11 in more than 3 cancer types. Because this analysis shows association rather than direction, both HSPB11-to-partner and partner-to-HSPB11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSPB11 versus CDC20 in OV, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPB11→partner) and Y-score (partner→HSPB11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CDC20 →	+0.956	+0.426	.005	.009	2	4
HNSC	UROD →	+0.681	+0.245	.001	<.001	3	3
LUAD	CXCL14 →	-2.133	-0.352	.001	<.001	3	3
OV	PTTG1 →	+1.007	+0.470	.005	.005	3	3
OV	SYNPO2 →	-0.804	-0.442	<.001	<.001	3	3
HNSC	RFC2 →	+0.701	+0.234	.003	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,371 associations by consensus.

HSPB11 vs CDC20 — OV

Explore this scatter interactively →