HSFY1P1

Q-omics provides the consensus-scored HSFY1P1 profile across patient tissues and cancer cell-line models. HSFY1P1 expression is associated with patient survival in 12 of 34 cancer types, with the highest sampling consensus in UVM. Additionally, HSFY1P1 RNA expression shows 4,992 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight UVM, and STAD as cancer lineages where HSFY1P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes HSFY1P1 survival associations across molecular data types. HSFY1P1 RNA expression shows survival associations in the most cancer types (12), followed by mutation status (3). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

HSFY1P1 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	12	UVM (108)	view →
Mutation	Kaplan–Meier	3	LUAD (39)	view →

This table ranks reproducible HSFY1P1 RNA expression–survival associations across cancer types. High HSFY1P1 expression shows unfavorable associations in UVM, UCS, STAD, OV and LIHC, but favorable associations in HNSC. The UVM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UVM as the clearest survival context for HSFY1P1 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	All	0.075	0.859	<.001	108	view →
UCS	OS	Tertile	All	0.135	0.687	.009	72	view →
STAD	DFS	Tertile	All	0.361	0.575	<.001	42	view →
OV	OS	Tertile	IV	0.059	0.759	.006	36	view →
HNSC	OS	Tertile	IV	1.000	0.378	.010	33	view →
LIHC	OS	Tertile	All	0.275	0.786	.002	24	view →

Pink = unfavorable, green = favorable. all 12 lineages →

HSFY1P1-UVM (OS)

Explore this curve interactively →