HOXC-AS3

Across TCGA patient cohorts, HOXC-AS3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,944 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible HOXC-AS3-associated GO terms across cancer lineages are Embryonic skeletal system morphogenesis, U2-type prespliceosome assembly, and Anterior/posterior pattern specification. Each is linked with HOXC-AS3 in more than 16 cancer types. Because this analysis shows association rather than direction, both HOXC-AS3-to-partner and partner-to-HOXC-AS3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Embryonic skeletal system morphogenesis grouped by HOXC-AS3-low versus HOXC-AS3-high in GBM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXC-AS3→partner) and Y-score (partner→HOXC-AS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	Embryonic skeletal system morphogenesis →	+0.038	+0.347	<.001	<.001	3	17
STAD	U2-type prespliceosome assembly →	+0.048	+0.385	<.001	<.001	3	16
STAD	Anterior/posterior pattern specification →	+0.033	+0.472	<.001	<.001	3	15
ACC	Proximal/distal pattern formation →	+0.072	+0.500	<.001	<.001	3	15
ACC	Negative regulation of chromosome organization →	+0.039	+0.236	<.001	.003	3	15
STAD	Regulation of DNA-templated DNA replication →	+0.036	+0.336	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,944 associations by consensus.

Embryonic skeletal system morphogenesis by HOXC-AS3 expression — GBM

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