HOPX

Across TCGA cell cohorts, HOPX RNA expression is significantly associated with the RNA expression of many other genes, with 6,241 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible HOPX-associated genes across cancer lineages are BANK1, SOWAHB, and GRHL3. Each is linked with HOPX in more than 4 cancer types. Because this analysis shows association rather than direction, both HOPX-to-partner and partner-to-HOPX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOPX versus BANK1 in BLOOD_Leukemia, with a Pearson correlation of 0.38.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HOPX→partner) and Y-score (partner→HOPX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	BANK1 →	+1.543	+1.950	<.001	.001	3	5
URINARY_TRACT	SOWAHB →	+1.887	+2.253	<.001	<.001	3	4
URINARY_TRACT	GRHL3 →	+2.528	+2.332	.001	.001	3	4
BONE	ARHGAP10 →	+1.985	+1.415	<.001	.001	3	4
URINARY_TRACT	ARHGDIB →	+3.648	+2.035	<.001	.001	3	4
LUNG_NSCLC_LUAD	TTC9 →	+1.714	+1.760	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,241 associations by consensus.

HOPX vs BANK1 — BLOOD_Leukemia

Explore this scatter interactively →