Q-omics provides the consensus-scored BANK1 profile across patient tissues and cancer cell-line models. BANK1 expression is associated with patient survival in 23 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, BANK1 is differentially expressed in 13, with the highest sampling consensus in LUAD. Additionally, BANK1 RNA expression shows 17,628 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight KIRC, LUAD, and THYM as cancer lineages where BANK1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for BANK1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes BANK1 survival associations across molecular data types. BANK1 RNA expression shows survival associations in the most cancer types (23), followed by mutation status (6) and mass-spec protein abundance (1). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible BANK1 RNA expression–survival associations across cancer types. High BANK1 expression shows unfavorable associations in KIRP and LGG, but favorable associations in KIRC, HNSC, SKCM and ACC. The KIRC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for BANK1 RNA expression.
This table summarizes BANK1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 13, while mass-spec protein shows differences in 4. The strongest signals are observed in LUAD for RNA and CCRCC for protein.
This table ranks reproducible tumor–normal expression differences for BANK1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. BANK1 shows lower tumor expression in LUAD, THCA, LUSC, KICH, BRCA and COAD. The LUAD box plot shows higher BANK1 RNA expression in normal versus tumor tissue (log2 FC = −1.331, t-test p < 0.001).
This table shows molecular features associated with BANK1 in patient tissues and cancer cell lines. In patient samples, BANK1 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set. In cancer cell lines, BANK1 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in BLOOD_Leukemia, while CRISPR and shRNA rows add functional-dependency signals in UPPER_AERODIGESTIVE_TRACT and BLOOD_Lymphoma.
