BANK1

Across TCGA cell cohorts, BANK1 mutation is significantly associated with the RNA expression of many other genes, with 88 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BANK1-associated genes across cancer lineages are CDY2A, PTGDR, and SPAG11A. Each is linked with BANK1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BANK1-to-partner and partner-to-BANK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDY2A grouped by BANK1-low versus BANK1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BANK1→partner) and Y-score (partner→BANK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	CDY2A →	+0.006	+6.247	<.001	<.001	3	1
SKIN	PTGDR →	+0.014	+3.930	<.001	.003	3	1
SKIN	SPAG11A →	+0.044	+4.437	<.001	.004	3	1
BLOOD_Leukemia	H1-1 →	+0.075	+4.359	.002	<.001	3	1
BLOOD_Leukemia	APOL5 →	+0.011	+4.475	.001	<.001	3	1
BLOOD_Leukemia	OR52Z1 →	+0.033	+3.969	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 88 associations by consensus.

CDY2A by BANK1 expression — BLOOD_Lymphoma

Explore this box plot interactively →