BANK1

Across TCGA pan-cancer cohorts, BANK1 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated BANK1 data layer compared with 23 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher BANK1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated BANK1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

HNSC, THYM, and UCEC are the cancer types where BANK1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	III,IV	0.119	0.746	<.001	24	view →
THYM	OS	Median	All	0.186	0.931	<.001	15	view →
UCEC	DFS	Median	All	0.973	0.828	.019	14	view →
LUAD	OS	Median	III,IV	0.314	0.666	.038	9	view →
PRAD	DFS	Median	All	0.584	0.886	.009	6	view →
COAD	OS	Median	III,IV	0.161	0.780	.013	6	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

BANK1–HNSC (OS)

Open the HNSC breakdown →