HOMER1

Across TCGA patient cohorts, HOMER1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,885 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HOMER1-associated proteins across cancer lineages are IRF4, RASAL3_S72, and RCSD1. Each is linked with HOMER1 in more than 4 cancer types. Because this analysis shows association rather than direction, both HOMER1-to-partner and partner-to-HOMER1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOMER1 versus IRF4 in UCEC, with a Pearson correlation of -0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HOMER1→partner) and Y-score (partner→HOMER1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IRF4 →	-0.782	-0.608	.002	.008	3	5
LSCC	RASAL3_S72 →	-0.600	-0.496	<.001	<.001	3	5
LSCC	RCSD1 →	-0.437	-0.497	<.001	<.001	3	4
LUAD	DNM2 →	-0.271	-0.590	<.001	<.001	3	4
UCEC	EVL_S246 →	-0.832	-0.803	<.001	<.001	3	4
GBM	HCLS1 →	-0.563	-0.454	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,885 associations by consensus.

HOMER1 vs IRF4 — UCEC

Explore this scatter interactively →