HNRNPA2B1

Across TCGA patient cohorts, HNRNPA2B1 mutation is significantly associated with the RNA expression of many other genes, with 2,325 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HNRNPA2B1-associated genes across cancer lineages are RNU4-58P, SNORD116-7, and KTN1-AS1. Each is linked with HNRNPA2B1 in more than 2 cancer types. Because this analysis shows association rather than direction, both HNRNPA2B1-to-partner and partner-to-HNRNPA2B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU4-58P grouped by HNRNPA2B1-low versus HNRNPA2B1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPA2B1→partner) and Y-score (partner→HNRNPA2B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU4-58P →	+0.176	+2.470	.001	.001	3	3
SKCM	SNORD116-7 →	+0.536	+2.711	<.001	.005	3	3
UCEC	KTN1-AS1 →	+0.283	+2.000	.008	.003	3	2
CESC	RNA5SP131 →	+0.352	+5.342	<.001	.002	3	2
BRCA	ARL2BPP6 →	+0.072	+4.971	.003	.005	3	2
BLCA	ZFAND1 →	+0.494	+3.707	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,325 associations by consensus.

RNU4-58P by HNRNPA2B1 expression — UCEC

Explore this box plot interactively →