Across TCGA patient cohorts, HMGB3P19 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,135 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HMGB3P19-associated GO terms across cancer lineages are Proteasome assembly, Microtubule cytoskeleton organization involved in mitosis, and Mitotic DNA integrity checkpoint signaling. Each is linked with HMGB3P19 in more than 7 cancer types. Because this analysis shows association rather than direction, both HMGB3P19-to-partner and partner-to-HMGB3P19 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB3P19→partner) and Y-score (partner→HMGB3P19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Proteasome assembly →	+0.100	+0.089	<.001	<.001	3	8
STAD	Microtubule cytoskeleton organization involved in mitosis →	+0.107	+0.089	<.001	<.001	3	7
STAD	Mitotic DNA integrity checkpoint signaling →	+0.094	+0.093	<.001	<.001	3	7
STAD	Protein targeting to mitochondrion →	+0.098	+0.093	<.001	<.001	3	7
STAD	Mitotic spindle organization →	+0.107	+0.101	<.001	<.001	3	7
STAD	Positive regulation of proteasomal protein catabolic process →	+0.098	+0.095	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,135 associations by consensus.

Exploration

HMGB3P19 survival (RNA) · tumor vs normal (RNA) · all HMGB3P19 data types