Across TCGA pan-cancer cohorts, HMGB3P19 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of HMGB3P19’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where HMGB3P19 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types HMGB3P19 is over-expressed in tumor.

LUAD are the cancer types where HMGB3P19 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in HMGB3P19 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	All	+0.018	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: HMGB3P19 RNA expression & survival · all HMGB3P19 data types