Across TCGA patient cohorts, HMGB1P9 RNA expression is significantly associated with the protein abundance of many other proteins, with 6,127 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HMGB1P9-associated proteins across cancer lineages are SND1_S781, MDM1_T515, and SETDB1_S1066. Each is linked with HMGB1P9 in more than 2 cancer types. Because this analysis shows association rather than direction, both HMGB1P9-to-partner and partner-to-HMGB1P9 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB1P9→partner) and Y-score (partner→HMGB1P9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SND1_S781 →	+0.577	+0.567	<.001	.001	3	3
BRCA	MDM1_T515 →	-0.571	-0.620	.001	.002	3	3
BRCA	SETDB1_S1066 →	+0.609	+0.528	.003	<.001	3	2
BRCA	TBC1D13_S184 →	-0.550	-0.516	.001	.006	3	2
OV	HECTD1_S1567 →	+0.909	+0.512	.005	.002	3	2
LUAD	METTL22_S132 →	-0.394	-0.105	.007	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,127 associations by consensus.

Exploration

HMGB1P9 survival (RNA) · tumor vs normal (RNA) · all HMGB1P9 data types