HMGA1P2

Across TCGA patient cohorts, HMGA1P2 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,144 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible HMGA1P2-associated GO terms across cancer lineages are Signal transduction in response to DNA damage, Mitotic DNA integrity checkpoint signaling, and Nucleotide-excision repair. Each is linked with HMGA1P2 in more than 31 cancer types. Because this analysis shows association rather than direction, both HMGA1P2-to-partner and partner-to-HMGA1P2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Signal transduction in response to DNA damage grouped by HMGA1P2-low versus HMGA1P2-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGA1P2→partner) and Y-score (partner→HMGA1P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Signal transduction in response to DNA damage →	+0.045	+0.616	.001	.003	3	32
THYM	Mitotic DNA integrity checkpoint signaling →	+0.049	+0.906	<.001	<.001	3	32
DLBC	Nucleotide-excision repair →	+0.046	+0.963	<.001	<.001	3	32
DLBC	Positive regulation of chromosome organization →	+0.058	+0.900	<.001	<.001	3	32
DLBC	Obsolete histone modification →	+0.059	+0.808	<.001	<.001	3	31
DLBC	Retrograde transport, vesicle recycling within Golgi →	+0.075	+1.020	<.001	<.001	3	31

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,144 associations by consensus.

Signal transduction in response to DNA damage by HMGA1P2 expression — DLBC

Explore this box plot interactively →