HAUS4

Across TCGA patient cohorts, HAUS4 protein abundance is significantly associated with the RNA expression of many other genes, with 9,707 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HAUS4-associated genes across cancer lineages are TTK, LMNB1, and NCAPH. Each is linked with HAUS4 in more than 6 cancer types. Because this analysis shows association rather than direction, both HAUS4-to-partner and partner-to-HAUS4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HAUS4 versus TTK in LUAD, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HAUS4→partner) and Y-score (partner→HAUS4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TTK →	+1.038	+0.290	<.001	<.001	3	7
OV	LMNB1 →	+1.201	+0.433	<.001	<.001	3	7
BRCA	NCAPH →	+0.874	+0.367	<.001	<.001	3	7
LUAD	CHEK1 →	+0.924	+0.286	<.001	<.001	3	7
OV	SPC25 →	+1.173	+0.453	<.001	<.001	3	7
LSCC	BUB1B →	+1.002	+0.321	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,707 associations by consensus.

HAUS4 vs TTK — LUAD

Explore this scatter interactively →