HAO2

Across TCGA patient cohorts, HAO2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,881 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible HAO2-associated genes across cancer lineages are KDELR3, MIOX, and CGRRF1. Each is linked with HAO2 in more than 1 cancer types. Because this analysis shows association rather than direction, both HAO2-to-partner and partner-to-HAO2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HAO2 versus KDELR3 in CCRCC, with a Pearson correlation of -0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HAO2→partner) and Y-score (partner→HAO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	KDELR3 →	-0.862	-0.629	<.001	<.001	3	1
CCRCC	MIOX →	+1.752	+0.563	<.001	.003	3	1
CCRCC	CGRRF1 →	+0.398	+0.497	<.001	.009	3	1
CCRCC	SERPINA4 →	-0.524	-0.529	.003	.002	3	1
CCRCC	FOXF1 →	+0.608	+0.695	.002	<.001	3	1
CCRCC	TRPA1 →	-0.520	-0.557	.002	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,881 associations by consensus.

HAO2 vs KDELR3 — CCRCC

Explore this scatter interactively →