H3C5P

Across TCGA patient cohorts, H3C5P RNA expression is significantly associated with the protein abundance of many other proteins, with 5,346 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible H3C5P-associated proteins across cancer lineages are URB2, SMARCC2_T322, and TOP2A_S1377. Each is linked with H3C5P in more than 2 cancer types. Because this analysis shows association rather than direction, both H3C5P-to-partner and partner-to-H3C5P results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, H3C5P versus URB2 in LSCC, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H3C5P→partner) and Y-score (partner→H3C5P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	URB2 →	+0.258	+0.467	<.001	.003	3	3
LSCC	SMARCC2_T322 →	+0.862	+0.630	<.001	<.001	3	3
CCRCC	TOP2A_S1377 →	+0.808	+0.281	.002	.001	3	3
COAD	ORC4 →	+0.367	+0.199	.007	.002	3	3
COAD	SF3B3 →	+0.207	+0.169	<.001	.003	3	3
LUAD	HMGB3 →	+0.638	+0.463	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,346 associations by consensus.

H3C5P vs URB2 — LSCC

Explore this scatter interactively →