H2BC8

Across TCGA patient cohorts, H2BC8 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,813 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible H2BC8-associated proteins across cancer lineages are RFC1_T506, RRM2_S20, and ATAD2_S342. Each is linked with H2BC8 in more than 4 cancer types. Because this analysis shows association rather than direction, both H2BC8-to-partner and partner-to-H2BC8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, H2BC8 versus RFC1_T506 in LUAD, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H2BC8→partner) and Y-score (partner→H2BC8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RFC1_T506 →	+0.816	+1.123	<.001	<.001	3	5
GBM	RRM2_S20 →	+1.099	+1.011	<.001	<.001	3	5
LUAD	ATAD2_S342 →	+1.640	+1.523	<.001	<.001	3	5
GBM	SMC2 →	+0.637	+0.925	<.001	<.001	3	5
GBM	SMC4 →	+0.612	+0.880	<.001	<.001	3	5
LUAD	TOP2A_S1106 →	+1.242	+1.420	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,813 associations by consensus.

H2BC8 vs RFC1_T506 — LUAD

Explore this scatter interactively →