Across TCGA patient cohorts, H2BC18 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,680 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible H2BC18-associated proteins across cancer lineages are RFC4, SMC4, and CHAF1A. Each is linked with H2BC18 in more than 6 cancer types. Because this analysis shows association rather than direction, both H2BC18-to-partner and partner-to-H2BC18 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H2BC18→partner) and Y-score (partner→H2BC18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RFC4 →	+0.472	+1.018	<.001	<.001	3	7
GBM	SMC4 →	+0.713	+0.994	<.001	<.001	3	7
UCEC	CHAF1A →	+0.602	+1.403	<.001	<.001	3	7
LSCC	CSTF3 →	+0.270	+0.681	<.001	<.001	3	7
CCRCC	KIF11_T926 →	+1.144	+1.022	<.001	.001	3	7
GBM	UBTF_S484 →	+1.035	+0.976	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,680 associations by consensus.

Exploration

H2BC18 survival (RNA) · tumor vs normal (RNA) · all H2BC18 data types