H2AL1RP

Across TCGA patient cohorts, H2AL1RP RNA expression is significantly associated with the go_rna of many other GO terms, with 5,468 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible H2AL1RP-associated GO terms across cancer lineages are Regulation of keratinocyte proliferation, Regulation of endocytic recycling, and Positive regulation of T cell tolerance induction. Each is linked with H2AL1RP in more than 5 cancer types. Because this analysis shows association rather than direction, both H2AL1RP-to-partner and partner-to-H2AL1RP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of keratinocyte proliferation grouped by H2AL1RP-low versus H2AL1RP-high in HNSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AL1RP→partner) and Y-score (partner→H2AL1RP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	Regulation of keratinocyte proliferation →	+0.017	+0.074	<.001	<.001	3	6
LGG	Regulation of endocytic recycling →	+0.046	+0.019	<.001	<.001	3	6
PAAD	Positive regulation of T cell tolerance induction →	-0.046	-0.330	.001	.002	3	5
HNSC	Keratinization →	+0.070	+0.110	<.001	<.001	3	5
HNSC	Sodium ion import across plasma membrane →	+0.029	+0.076	<.001	<.001	3	5
LGG	Negative regulation of inclusion body assembly →	+0.055	+0.015	<.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,468 associations by consensus.

Regulation of keratinocyte proliferation by H2AL1RP expression — HNSC

Explore this box plot interactively →