H2AL1RP

Across TCGA pan-cancer cohorts, H2AL1RP RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated H2AL1RP data layer.

The strongest signal is observed in thymoma (THYM), where higher H2AL1RP RNA is associated with worse overall survival. In most high-consensus cancer types, elevated H2AL1RP expression acts as an unfavorable survival marker, although some lineages such as THCA and BLCA show a favorable association.

THYM, LUSC, and OV are the cancer types where H2AL1RP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Tertile	All	0.611	0.901	<.001	36	view →
LUSC	OS	Tertile	IV	0.001	0.673	.014	36	view →
OV	DFS	Tertile	All	0.113	0.176	.023	36	view →
KIRC	OS	Tertile	All	0.756	0.879	.036	24	view →
SARC	DFS	Tertile	All	0.181	0.635	.007	21	view →
THCA	OS	Median	II,III,IV	1.000	0.932	.016	16	view →
BLCA	DFS	Tertile	All	0.645	0.239	.006	16	view →
SKCM	OS	Tertile	All	0.498	0.281	.016	15	view →
LUAD	OS	Tertile	II,III,IV	0.335	0.489	.024	14	view →
READ	DFS	Tertile	IV	0.240	0.715	<.001	12	view →
GBM	DFS	Tertile	All	0.090	0.304	.002	9	view →
STAD	OS	Tertile	All	0.291	0.619	.036	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

H2AL1RP–THYM (OS)

Open the THYM breakdown →