H2AL1RP

Across TCGA pan-cancer cohorts, H2AL1RP RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of H2AL1RP’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where H2AL1RP RNA is more highly expressed in tumor relative to normal tissue. In most cancer types H2AL1RP is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

THCA, BRCA, and KIRC are the cancer types where H2AL1RP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in H2AL1RP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Female	All	+0.266	<.001	7	view →
BRCA	All	II,III,IV	+0.115	<.001	6	view →
KIRC	All	All	−0.042	.001	6	view →
LUSC	All	All	+0.085	.001	4	view →
BLCA	All	All	+0.087	.044	2	view →
PRAD	All	All	+0.017	.038	2	view →
KICH	All	All	−0.122	.009	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

H2AL1RP–THCA

Open the THCA breakdown →