Q-omics provides the consensus-scored H2AL1RP profile across patient tissues and cancer cell-line models. H2AL1RP expression is associated with patient survival in 17 of 34 cancer types, with the highest sampling consensus in OV. Among the 18 cancer types available for tumor–normal comparison, H2AL1RP is differentially expressed in 7, with the highest sampling consensus in THCA. Additionally, H2AL1RP RNA expression shows 6,900 significant gene co-expression associations, with the highest sampling consensus in LGG. Together, these results highlight OV, THCA, and LGG as cancer lineages where H2AL1RP shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for H2AL1RP — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes H2AL1RP survival associations across molecular data types. H2AL1RP RNA expression shows survival associations in the most cancer types (17). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible H2AL1RP RNA expression–survival associations across cancer types. High H2AL1RP expression shows unfavorable associations in OV, THYM, LUSC, KIRC and SARC, but favorable associations in THCA. The OV Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .023). Together, the overview and detailed table identify OV as the clearest survival context for H2AL1RP RNA expression.
This table summarizes H2AL1RP tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 7. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for H2AL1RP. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. H2AL1RP shows lower tumor expression in KIRC and higher tumor expression in THCA, BRCA, LUSC, BLCA and PRAD. The THCA box plot shows higher H2AL1RP RNA expression in tumor versus normal tissue (log2 FC = +0.266, t-test p < 0.001).
This table shows molecular features associated with H2AL1RP in patient tissues and cancer cell lines. In patient samples, H2AL1RP shows the broadest associations at the RNA and protein expression levels, with LGG recurring as the lineage with the largest associated feature set.
