H2AJ

Across TCGA patient cohorts, H2AJ protein abundance is significantly associated with the RNA expression of many other genes, with 91 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible H2AJ-associated genes across cancer lineages are WASF1, IVNS1ABP, and MOB3B. Each is linked with H2AJ in more than 1 cancer types. Because this analysis shows association rather than direction, both H2AJ-to-partner and partner-to-H2AJ results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, H2AJ versus WASF1 in BRCA, with a Pearson correlation of -0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AJ→partner) and Y-score (partner→H2AJ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	WASF1 →	-1.388	-1.163	.002	.005	3	1
BRCA	IVNS1ABP →	-0.888	-1.148	.003	.006	3	1
BRCA	MOB3B →	-1.875	-1.551	<.001	.005	3	1
BRCA	RFXAP →	-0.928	-1.148	.002	.006	3	1
BRCA	URB2 →	-0.716	-1.123	.001	.007	3	1
BRCA	EGLN1 →	-0.891	-1.223	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 91 associations by consensus.

H2AJ vs WASF1 — BRCA

Explore this scatter interactively →