GTF3A

Across TCGA patient cohorts, GTF3A protein abundance is significantly associated with the RNA expression of many other genes, with 4,864 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible GTF3A-associated genes across cancer lineages are POLR1D, ZDHHC20, and IL1RL1. Each is linked with GTF3A in more than 3 cancer types. Because this analysis shows association rather than direction, both GTF3A-to-partner and partner-to-GTF3A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GTF3A versus POLR1D in BRCA, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF3A→partner) and Y-score (partner→GTF3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	POLR1D →	+0.557	+0.376	<.001	.001	3	4
COAD	ZDHHC20 →	+0.799	+0.621	<.001	.001	3	3
UCEC	IL1RL1 →	-1.037	-0.292	<.001	.001	3	3
CCRCC	ATOH8 →	-0.763	-0.363	<.001	<.001	3	3
BRCA	PHYH →	-0.605	-0.280	.001	.003	3	3
LUAD	TRIM2 →	-0.935	-0.408	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,864 associations by consensus.

GTF3A vs POLR1D — BRCA

Explore this scatter interactively →