GSTA3

Across TCGA patient cohorts, GSTA3 mutation is significantly associated with the RNA expression of many other genes, with 88 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GSTA3-associated genes across cancer lineages are RNU6-1169P, RNA5SP461, and RNA5SP420. Each is linked with GSTA3 in more than 1 cancer types. Because this analysis shows association rather than direction, both GSTA3-to-partner and partner-to-GSTA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1169P grouped by GSTA3-low versus GSTA3-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GSTA3→partner) and Y-score (partner→GSTA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-1169P →	+0.569	+5.362	<.001	.005	3	2
HNSC	RNA5SP461 →	+0.247	+7.954	<.001	.008	3	2
UCEC	RNA5SP420 →	+0.813	+2.967	<.001	.002	3	2
CESC	VN2R9P →	+0.038	+5.201	.007	.007	3	1
CESC	MTND6P16 →	+0.075	+6.837	<.001	<.001	3	1
CESC	LINC02411 →	+0.105	+6.342	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 88 associations by consensus.

RNU6-1169P by GSTA3 expression — SKCM

Explore this box plot interactively →