GSTA3

Across TCGA pan-cancer cohorts, GSTA3 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of GSTA3’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where GSTA3 RNA is repressed in tumor relative to normal tissue. In most cancer types GSTA3 is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.

LUAD, LUSC, and KIRP are the cancer types where GSTA3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GSTA3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	III,IV	−1.883	<.001	9	view →
LUSC	Female	All	−1.589	<.001	8	view →
KIRP	All	II,III,IV	−0.111	<.001	8	view →
KICH	All	II,III,IV	+1.484	<.001	7	view →
STAD	Male	IV	−1.900	<.001	6	view →
BRCA	All	II,III,IV	+0.311	.032	4	view →
UCEC	All	All	−1.568	.016	2	view →
PRAD	All	All	+0.187	.029	2	view →
COAD	Female	All	−0.022	.008	2	view →
KIRC	All	All	−0.026	.044	1	view →
THCA	All	All	+0.021	.038	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

GSTA3–LUAD

Open the LUAD breakdown →