Q-omics provides the consensus-scored MTND6P16 profile across patient tissues and cancer cell-line models. MTND6P16 expression is associated with patient survival in 8 of 34 cancer types, with the highest sampling consensus in LUAD. Among the 18 cancer types available for tumor–normal comparison, MTND6P16 is differentially expressed in 2, with the highest sampling consensus in LUAD. Additionally, MTND6P16 RNA expression shows 7,956 significant gene co-expression associations, with the highest sampling consensus in THCA. Together, these results highlight LUAD, and THCA as cancer lineages where MTND6P16 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MTND6P16 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MTND6P16 survival associations across molecular data types. MTND6P16 RNA expression shows survival associations in the most cancer types (8). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MTND6P16 RNA expression–survival associations across cancer types. High MTND6P16 expression shows unfavorable associations in LUAD, BRCA, THCA, KIRC, PAAD and KIRP. The LUAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify LUAD as the clearest survival context for MTND6P16 RNA expression.
This table summarizes MTND6P16 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for MTND6P16. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MTND6P16 shows lower tumor expression in LUAD and KIRC. The LUAD box plot shows higher MTND6P16 RNA expression in normal versus tumor tissue (log2 FC = −0.014, t-test p = .048).
This table shows molecular features associated with MTND6P16 in patient tissues and cancer cell lines. In patient samples, MTND6P16 shows the broadest associations at the RNA and protein expression levels, with THCA recurring as the lineage with the largest associated feature set.
