GSN-AS1

Across TCGA patient cohorts, GSN-AS1 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. COAD shows the largest number of these associations.

The most reproducible GSN-AS1-associated genes across cancer lineages are OR11H12, MIR412, and RNU6-895P. Each is linked with GSN-AS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GSN-AS1-to-partner and partner-to-GSN-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR11H12 grouped by GSN-AS1-low versus GSN-AS1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GSN-AS1→partner) and Y-score (partner→GSN-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	OR11H12 →	+0.049	+7.741	<.001	.009	3	2
UCEC	MIR412 →	+0.621	+8.066	<.001	.007	3	1
COAD	RNU6-895P →	+0.396	+7.741	<.001	.009	3	1
COAD	RNU6-297P →	+0.387	+7.741	<.001	.009	3	1
COAD	MIR217 →	+0.369	+7.741	<.001	.009	3	1
COAD	RNU7-176P →	+0.537	+7.741	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

OR11H12 by GSN-AS1 expression — COAD

Explore this box plot interactively →