GSG1L

Across TCGA patient cohorts, GSG1L mutation is significantly associated with the RNA expression of many other genes, with 579 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GSG1L-associated genes across cancer lineages are SMIM11P1, ATF4P1, and SEZ6L-AS1. Each is linked with GSG1L in more than 2 cancer types. Because this analysis shows association rather than direction, both GSG1L-to-partner and partner-to-GSG1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SMIM11P1 grouped by GSG1L-low versus GSG1L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GSG1L→partner) and Y-score (partner→GSG1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SMIM11P1 →	+0.396	+2.491	<.001	<.001	3	3
UCEC	ATF4P1 →	+0.028	+2.132	.005	.009	3	3
LUSC	SEZ6L-AS1 →	+0.097	+4.780	<.001	.003	3	3
LIHC	SNORD114-4 →	+0.397	+5.317	<.001	.002	3	2
LIHC	MIR454 →	+0.191	+4.293	<.001	.009	3	2
LIHC	RNA5SP371 →	+0.221	+5.910	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 579 associations by consensus.

SMIM11P1 by GSG1L expression — UCEC

Explore this box plot interactively →